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A drug is, in the broadest of terms, a chemical substance that has known biological effects on humans or other animals. foods are generally excluded from this.A (named a / ˈ eɪ /, plural aes) is the first letter and vowel in the iso basic latin alphabet it is similar to the ancient greek letter alpha, from which it derives..The principles of the use of the definite article in english are described above under use of articles. (the word the is also used with comparatives, in phrases like. The use of profanity in films has always been controversial, but has increased significantly in recent years. the use of the word fuck in film has always drawn.